| Term
Name |
Definition |
View
Report |
|
(C-C motif) ligand 21 [CCL-21] cDNA
|
( C-C motif) ligand 21 or CCL21 is one of several CC cytokine genes clustered on the p-arm of chromosome 9. The CC cytokines are proteins characterized by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. It is a high affinity functional ligand for chemokine receptor 7 (CCR7) that is expressed on T and B lymphocytes and a known receptor for another member of the cytokine family (small inducible cytokine A19). [provided by RefSeq] - see also Human Genome Organization - Nomenclature Committee (HGNC) #HGNC:10620; GenBank Accession NM_002989.
|
 |
|
17 aa Adenovirus E3/19K leader sequence
|
Endoplasmic Reticulum insertion signal sequnce derived from the Adenovirus E3 transcriptional region encoding the the 19 Kdal protein
|
|
|
3' untranslated region
|
|
|
|
3’ splice site
|
RNA splicing is a process that removes introns and joins exons in a primary transcript. An intron usually contains a clear signal for splicing. Most introns start from the sequence GU and end with the sequence AG (in the 5' to 3' direction).
|
|
|
5' and 3' splice sites
|
|
|
|
5’ and 3’ Adeno-associated virus inverted terminal repeat
|
|
|
|
5’ intron intervening sequence 8
|
|
|
|
5’ untranslated region and coding sequence for first four amino acids of rat insulin II leader peptide
|
|
|
|
5’ untranslated region and leader sequence for tissue plasminogen activator
|
|
|
|
5T4 oncofetal antigen cDNA - human
|
5T4 is a 72 kDa oncofoetal glycoprotein that is expressed on over 70% of carcinomas of the kidney, breast, gastrointestinal tract, colon and ovaries. Unlike other self-antigen tomor associated antigens (TAAs) such as CEA, 5T4 expression as detected by histochemical staining appears to be tumour specific with only low level sporadic staining observed in the gut and pituitary.
|
|