GeMCRIS - Genetic Element Hierarchy Reports
The Genetic Modification Clinical Research Information System Version 6.1 Site Map Link

Search by Term Name, Definition, or Term Synonym. The search box below will find results based on the exact characters entered. Entering multiple words in the search box may limit your results.

Click a 'View' button to display the definition and synonyms for that term or click 'View All' to display all 637 terms listed below.
View All
Records 1 to 10 of 637
Genetic Element Hierarchy Reports
Next
Term Name Definition View Report
(C-C motif) ligand 21 [CCL-21] cDNA   ( C-C motif) ligand 21 or CCL21 is one of several CC cytokine genes clustered on the p-arm of chromosome 9. The CC cytokines are proteins characterized by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. It is a high affinity functional ligand for chemokine receptor 7 (CCR7) that is expressed on T and B lymphocytes and a known receptor for another member of the cytokine family (small inducible cytokine A19). [provided by RefSeq] - see also Human Genome Organization - Nomenclature Committee (HGNC) #HGNC:10620; GenBank Accession NM_002989.   View
17 aa Adenovirus E3/19K leader sequence   Endoplasmic Reticulum insertion signal sequnce derived from the Adenovirus E3 transcriptional region encoding the the 19 Kdal protein   View
3' untranslated region     View
3’ splice site   RNA splicing is a process that removes introns and joins exons in a primary transcript. An intron usually contains a clear signal for splicing. Most introns start from the sequence GU and end with the sequence AG (in the 5' to 3' direction).   View
5' and 3' splice sites     View
5’ and 3’ Adeno-associated virus inverted terminal repeat     View
5’ intron intervening sequence 8     View
5’ untranslated region and coding sequence for first four amino acids of rat insulin II leader peptide     View
5’ untranslated region and leader sequence for tissue plasminogen activator     View
5T4 oncofetal antigen cDNA - human   5T4 is a 72 kDa oncofoetal glycoprotein that is expressed on over 70% of carcinomas of the kidney, breast, gastrointestinal tract, colon and ovaries. Unlike other self-antigen tomor associated antigens (TAAs) such as CEA, 5T4 expression as detected by histochemical staining appears to be tumour specific with only low level sporadic staining observed in the gut and pituitary.   View